Some of the more serious side effects include loss of sex drive, impotence, weakened bones , and heart problems. Treatments that slow the spread of advanced prostate cancer and is the first treatment usually offered if the cancer has spread. But doctors do have ways to help control its spread and related symptoms. Currently, no treatments can cure advanced prostate cancer. Cancer that spreads outside the prostate gland to the lymph nodes, bones, or other areas is called metastatic prostate cancer. Prostate cancer occurs when a tumor develops in the prostate health gland, which makes the liquid portion of semen. Select a topic to explore more. Send your greetings of the season and support the Prostate Cancer Foundation at the same time. Click here for a list of additional open trials. This study is being conducted in over 50 centers across the USA and also in 24 other countries around the world. Ipilimumab plus radiotherapy will be compared to placebo plus radiotherapy in this randomized, double-blind study, to determine if ipilimumab prolongs survival in men who have metastatic CRPC.